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Some cold medications can be taken at the same time without issue, but other combinations can pose safety concerns. Most multi-symptom cold and cough medications should not be combined with each other. If you need to take more than one medication at a time, always check the labels and be sure you aren't taking multiple medications with the same or similar active ingredients.
If you are taking single symptom medications, in general, it is OK to take several medications as long as they do different things. For example, taking a decongestant, expectorant, and pain reliever would be OK, but taking two decongestants would not. To help make it a little simpler, the following is a list of some of the most common OTC cold and flu medications that are available in the U.
Review which ones can safely be combined and which ones you shouldn't mix. If you don't see the medications you want to take on the list, talk to your healthcare provider or pharmacist to ensure it's safe to combine with others.
Possible active ingredients:. Alternating with ibuprofen is OK as long as you are not taking more acetaminophen than is recommended in a hour period or with each dose. Many multi-symptom medications also contain acetaminophen and should not be taken with Tylenol or generic acetaminophen.
Always read the ingredient label on the medications you are taking. Do not take more than one medication that contains the active ingredient acetaminophen. The U. Food and Drug Administration warns of the danger of accidentally overdosing on acetaminophen when taking multiple OTC cold and flu medications that contain it. An overdose can cause irreparable liver damage and even lead to death. Alternating with acetaminophen is OK as long as you are not taking more than is recommended of each medication in a hour period or with each dose.
There are not as many multi-symptom medications that contain ibuprofen as compared to acetaminophen, but you should always review the labels anyway. Aspirin should not be combined with other pain relievers unless specifically instructed by a healthcare provider. Pepto-Bismol also contains a derivative of aspirin and should be used with caution if you are taking aspirin. Medications containing aspirin and salicylates should never be given to a child or teen under age 19 unless specifically instructed by their healthcare provider.
When taken during a viral illness, it can cause Reye's syndrome and harm the liver and brain. Naproxen should not be combined with other pain relievers unless specifically directed by your healthcare provider. The active ingredient in Robitussin is dextromethorphan. How well this medication works is debatable, but it should not be combined with other medications that contain a cough suppressant.
Always read the label of every medication you take. Many multi-symptom cold and cough remedies contain guaifenesin—the active ingredient in Mucinex. There are many others. The CDC warns that OTC cough and cold medicines should not be given to a child younger than 4 years unless directed by their healthcare provider. They can result in serious side effects that can be life-threatening. Consult your healthcare provider about the safety of these products for children age 4 and over.
Always look at the active ingredients and do not combine Sudafed with other medications containing phenylephrine, pseudoephedrine, or decongestants. Benadryl should not be combined with other antihistamines unless specifically instructed by your healthcare provider. Additionally, it should not be combined with topical Benadryl cream. Always look at the active ingredients and do not combine medications that contain diphenhydramine or other antihistamines.
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